Ricerca e Innovazione

HairScience Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles.

Italian Survey for the Evaluation of the Effects of Coronavirus Disease 2019 (COVID-19) Pandemic on Alopecia Areata Recurrence Predictive metagenomic profiling, urine metabolomics, and human marker gene expression as an integrated approach to study alopecia areata Efficacy of Postbiotics in a PRP-Like Cosmetic Product for the Treatment of Alopecia Area Celsi: A Randomized Double-Blinded Parallel-Group Study ‘Omics’ approaches for studying the microbiome in Alopecia areata 598 Increasing follicular resistance to bacterial contamination: A novel antimicrobial therapy? Scalp bacterial shift in Alopecia areata.
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2018

Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles.

PLoS Biol 2018; 16 (5): e2003705.

Hair growth disorders often carry a major psychological burden. Therefore, more effective human hair growth±modulatory agents urgently need to be developed. Here, we used the hypertrichosis-inducing immunosuppressant, Cyclosporine A (CsA), as a lead compound to identify new hair growth±promoting molecular targets.

Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles.

Hawkshaw NJ et al.