{"id":539,"date":"2020-05-13T18:05:47","date_gmt":"2020-05-13T16:05:47","guid":{"rendered":"https:\/\/www.hairsciencegiuliani.com\/pubblicazioni\/n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles\/"},"modified":"2020-05-13T18:05:47","modified_gmt":"2020-05-13T16:05:47","slug":"n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles","status":"publish","type":"pubblicazioni","link":"https:\/\/www.hairsciencegiuliani.com\/en\/pubblicazioni\/n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles\/","title":{"rendered":"N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles."},"content":{"rendered":"<p>Spermidine (Spd), the prototypic polyamine,has been shown to be essential for hair follicle (HF)growth. However, Spd can be readily converted into other polyamines, and is physiologically unstable.Therefore, to assess its individual functions on HFs, we used the metabolically stable Spd analog N1-methyl spermidine (N1-MeSpd).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Spermidine (Spd), the prototypic polyamine,has been shown to be essential for hair follicle (HF)growth. However, Spd can be readily converted into other polyamines, and is physiologically unstable.Therefore, to assess its individual functions on HFs, we used the metabolically stable Spd analog N1-methyl spermidine (N1-MeSpd).<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false},"class_list":["post-539","pubblicazioni","type-pubblicazioni","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles. - Hair Science Giuliani<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.hairsciencegiuliani.com\/en\/pubblicazioni\/n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles. - Hair Science Giuliani\" \/>\n<meta property=\"og:description\" content=\"Spermidine (Spd), the prototypic polyamine,has been shown to be essential for hair follicle (HF)growth. However, Spd can be readily converted into other polyamines, and is physiologically unstable.Therefore, to assess its individual functions on HFs, we used the metabolically stable Spd analog N1-methyl spermidine (N1-MeSpd).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.hairsciencegiuliani.com\/en\/pubblicazioni\/n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles\/\" \/>\n<meta property=\"og:site_name\" content=\"Hair Science Giuliani\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.hairsciencegiuliani.com\/en\/pubblicazioni\/n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles\/\",\"url\":\"https:\/\/www.hairsciencegiuliani.com\/en\/pubblicazioni\/n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles\/\",\"name\":\"N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles. - Hair Science Giuliani\",\"isPartOf\":{\"@id\":\"https:\/\/www.hairsciencegiuliani.com\/en\/#website\"},\"datePublished\":\"2020-05-13T16:05:47+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.hairsciencegiuliani.com\/en\/pubblicazioni\/n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.hairsciencegiuliani.com\/en\/pubblicazioni\/n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.hairsciencegiuliani.com\/en\/pubblicazioni\/n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.hairsciencegiuliani.com\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.hairsciencegiuliani.com\/en\/#website\",\"url\":\"https:\/\/www.hairsciencegiuliani.com\/en\/\",\"name\":\"Hair Science Giuliani\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.hairsciencegiuliani.com\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles. - Hair Science Giuliani","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.hairsciencegiuliani.com\/en\/pubblicazioni\/n1-methylspermidine-a-stable-spermidine-analog-prolongs-anagen-and-regulates-epithelial-stem-cell-functions-in-human-hair-follicles\/","og_locale":"en_US","og_type":"article","og_title":"N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles. - Hair Science Giuliani","og_description":"Spermidine (Spd), the prototypic polyamine,has been shown to be essential for hair follicle (HF)growth. 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